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The study sample was drawn from all Newport News ladies dating online stroke cases occurring between January 5,Davenport dating guy December 31, During the study period, 1, patients with first-ever stroke survived 90 days after stroke, among whom 1, We then sequentially excluded with proxy baseline interview, who did not participate in the outcome interview, 23 with proxy outcome interview, and 9 without depression assessment, which le to a final sample of participants figure.

Although the massage Huntsville meeting difference did not reach statistical ificance in the present sample, possibly due to low power, there is biological plausibility for this finding. A sex difference in depression is found in the general population, with women at higher risk compared with men due to a variety of biological and psychosocial factors. We found psychomotor changes occurred more frequently in men, whereas somatic symptoms occurred more frequently in women, which is consistent with existing findings of sex differences in depression symptomatology.

Our findings showed that among stroke survivors on medication for depression at the time of stroke, women had ificantly lower risk for depression at 90 days poststroke compared with men, which may be explained by differential drug response due to sex differences in depression characteristics.

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In the study sample, the median time of the baseline interview was 7 days poststroke interquartile range, 13 daysand the median time of the outcome interview was swingers Hickory free days poststroke interquartile range, 13 days. Our study also suggests potential sex differences in the prevalence of individual depressive symptoms among participants with depression at 90 days after stroke. Our study has several limitations. Existing evidence shows that women are more likely to have depression after stroke than men, 27 but the vast majority of studies have been hospital-based and were not specifically deed to assess sex differences.

Try out PMC Labs and tell us what you think. Possible cases undergo blinded validation by stroke neurologists. Sex male, femalethe primary independent variable, and other covariates were ascertained at baseline from interviews or medical records. Depression affects approximately one-third of stroke survivors, and is associated with morbidity and disability. In the fully adjusted model, factors associated with depression after stroke included prestroke depression status, age, education, of medical asian ladies dating Santa Ana CA, and current smoking at baseline table 3.

There was no statistically ificant sex difference in depression after stroke among participants with no history of depression before stroke OR, 1. Prestroke and poststroke depression assessment are not available in proxy ginger dating San Juan, hence data are missing for these participants.

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Among dating nude Topeka women with a history of depression before stroke, women tended to have higher odds than men OR, 1. Interventions to address and prevent poststroke depression are needed, particularly among those with prestroke depression but not undergoing treatment for depression at stroke onset. Self-reported prestroke depression status was ascertained from the nonproxy baseline interviews.

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Covariates evaluated as potential confounders were sociodemographic, stroke, and prestroke characteristics. It is also worth mentioning that women were ificantly more Lafayette LA law dating to have a history of depression before stroke and to use medication for depression at the time of stroke, and prestroke depression status was strongly associated with depression after stroke, consistent with research.

To examine potential effect modification by prestroke depression status, we introduced interaction terms between sex and prestroke depression status to model 3, calculated stratum-specific odds ratios ORsand tested the ificance of the interaction using an F test 2 degrees of freedom. Compared with participants with nonproxy baseline interviews, those with proxy interviews were older, more likely to be widowed, more likely to be functionally and cognitively impaired, and more likely to have more medical conditions and cardiovascular risk factors table e However, such differences were not Corpus in outcome interview participation table e There was no statistically ificant sex difference between participants with and without missing data on baseline cognitive function table seeking, doi.

Factors associated with first-onset depression after first-ever stroke included being uninsured, of medical conditions, and current smoking at the time of stroke onset table e-6, doi. from the sensitivity analysis for the potentially not missing at random covariate data were consistent with the main findings table man, doi.

The present study aimed to contribute to existing literature by 1 examining the sex difference in prevalence Haven t date this man depression at 90 days after first-ever stroke in a population-based stroke study; 2 investigating the moderating role of prestroke depression in this association; and 3 ing for potential differential attrition to reduce selection bias.

We Christi conducted a separate analysis among participants with no history of depression by fitting a model with adjustment for sociodemographic, stroke, and prestroke characteristics, to examine risk factors for first onset of depression after stroke. To understand the possible influence of our missing data approach on thewe conducted complete case analysis and analysis with multiple imputation only, and compared the woman our primary analysis.

First, prestroke depression status was based on self-report of prior diagnoses and treatment rather than direct depression assessment, and therefore subject to misclassification due to recall bias and social desirability bias, and influenced by sex-specific help-seeking behaviors. The mean PHQ-8 score at 90 days poststroke was 6. Logistic regression was used to examine the legal dating age in Vallejo between sex and depression after stroke, and effect modification by prestroke depression status, ing for missing data.

Learn More. However, there were no statistically ificant sex differences in prestroke disability and cognitive impairment.

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Because depression is a risk factor for stroke and is more prevalent in women, 56 adequately treating women Myrtle MS flirting review depression may serve as a prevention strategy to both reduce risk of stroke and lessen poststroke depression in this high-risk group. We did not find a sex difference in first onset of depression after first-ever stroke.

Sex difference in prevalence of depression after stroke

Proxy interviews are conducted if patients with stroke are unconsentable, comatose, unresponsive, or unable to speak or communicate. Poststroke depressive symptoms were assessed by the 8-item Patient Health Questionnaire, and prestroke depression status history and medication use was self-reported. These should be considered as hypothesis generating.

PHQ-8 is an abbreviated version of local Manchester girl PHQ-9, which is a validated screening instrument for depression among stroke survivors.

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Among individuals prone to stroke, vascular risk factors may lead to late-onset depression through neural disconnectivity, hypoperfusion, and inflammation. Participants were asked whether they had ever been told by a doctor they had depression, and whether they were currently taking or had ever taken medications indians in Clarksville dating depression.

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However, we identified ificant effect modification of the association between sex and depression after stroke by prestroke depression status such that compared with men, women on medication for depression at the time of stroke were ificantly protected against depression after stroke, whereas women with depression history but not on medication showed a tendency for elevated risk compared with men.

The sex difference in prevalence of depression at 90 days after first-ever stroke was not ificant overall, but varied by prestroke depression status.

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Data from excluded patients were used in the analytical process to for potential differential attrition. We dealt with missing data using an approach combining multiple imputation and inverse probability weighting. After adjustment for attrition, the prevalence of depression as defined by a PHQ-8 score of 10 or higher at 90 days after first-ever stroke was Fatigue and sleep disturbance were the most common depressive symptoms in both men and Irving TX guy dating girl.

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To better understand sex differences in poststroke depression, it is necessary to take prestroke depression into consideration. Future research on treatment for poststroke depression may need to consider potential sex-specific treatment response, given the sex differences in etiologies, pathophysiology and severity of depression.

Associated data

Compared with men, women in this subset online dating johnstown Frederick MD older, were more likely to be widowed, and had greater stroke severity and more medical conditions. Notably, approximately one-fourth of women were on medication for depression at the time of stroke, and one-fifth of women were not on medication for depression but reported history of depression, which were ificantly higher than estimates in men.

Future studies with clinical examinations and biomedical tests could further investigate sex differences in the depressive phenotype and genotype among patients with stroke, which might aid in the development of better screening tools for poststroke depression. This study investigated the sex difference in prevalence of depression at 90 days after first-ever stroke.

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Sex differences in prevalence of depression and individual cute date ideas Newport News VA symptoms at 90 days poststroke, Brain Attack Surveillance in Corpus Christi project, United States, — As presented in table 3the age-adjusted OR of depression after stroke comparing women with men OR, 1.

Stroke characteristics included stroke type ischemic stroke, intracerebral hemorrhage stroke and initial stroke severity measured by the NIH Stroke Scale. Participants not on Salem boy dating profile for depression at the time of stroke were classified as having a history of depression if they reported having ever been diagnosed with depression or taken medications for depression; otherwise they were classified as no history of depression.

This study investigated the sex difference in prevalence of depression at 90 days after first-ever stroke in a population-based sample. Women were less likely than men to report history of coronary artery disease, excessive alcohol use, and smoking. We generated 3 mutually exclusiveincluding no history of depression, history of depression and on medication for depression at the time of stroke. Comparing sample characteristics between included and excluded participants, there was no statistically ificant sex difference in study participation at baseline table e-1, doi.

The prevalence of fatigue and appetite changes was higher meet friends Newport women than in men whereas the prevalence of psychomotor changes was higher in men than in women table 2. We found that women with prestroke depression but not on medication for depression at the time of stroke tended to have higher risk for depression after stroke than men. We conducted 2 sensitivity analyses. The data will not be made publicly available Utah meet girl of their restricted geek dating Raleigh NC.

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Existing findings from studies excluding patients with a history of depression are mixed, 27 with some evidence suggesting higher risk in women at 3 months poststroke. The percentage of missing covariate data was the greatest for baseline cognitive function We compared sample characteristics between included and excluded patients for each date in Fredericksburg us attrition step, and between study participants with and without missing data on baseline cognitive function.

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However, among participants on medication for depression at the time girls looking for sex Atlanta Georgia stroke, women were ificantly less likely to have depression at 90 days after stroke than men OR, 0. The nonificant overall association was therefore attributable to the heterogeneity according to prestroke depression status. Among participants on medication for depression at the time of stroke, women were ificantly less likely to have depression at 90 days compared with men OR, 0.

Our investigation of the influence of missing data suggests that the estimates of the sex difference would have been biased without ing for online dating for Lauderdale MN attrition due to women's worse stroke outcomes and higher propensity for depression. Statistical analyses were completed with Stata version Written informed consents were provided by patients or their surrogates. To consider potential violation of the missing at random assumption for multiple imputation of missing covariate data, we modeled the probability of missing baseline cognitive measures as dependent on the cognitive score itself.

Larger studies should seek to replicate these findings, particularly our finding of effect modification, with consideration for potential selection bias. As speed date Richmond VA in table 1women and men were approximately equally distributed in the study sample, with a mean age of Nearly three-fifths were Mexican American and two-fifths were non-Hispanic white. We used weighted cross-tabulations to estimate sex-specific prevalence of depression and each depressive symptom at 90 days poststroke.

of medical conditions was calculated by counting the following conditions: coronary artery disease, atrial fibrillation, congestive heart failure, diabetes, hypertension, high cholesterol, dementia, epilepsy, Parkinson disease, cancer, chronic obstructive pulmonary disease, and end-stage renal disease.

Using complete cases alone may cause selection bias in the presence of unmeasured factors that influence both the probability of remaining in the study and poststroke depression. We found that there was no statistically Chicago Illinois IL men dating women sex difference in prevalence of depression after ing for attrition.

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Patients with validated stroke are invited to participate in structured interviews in person shortly after stroke onset baseline interview and approximately 90 days after the index stroke outcome interview. This indicates they might have higher levels of beneficial characteristics than men that protected them from depression after stroke, such as social support. Effect modification of the association between sex and depression after stroke by prestroke depression status was Spartanburg free calling online after adjustment for all covariates table 4.

We checked functional forms of continuous covariates using locally weighted scatterplot smoothing, and applied appropriate terms respectively.

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Compared with the main free call girl in Vallejo CA, the age-adjusted OR was stronger and ificant among cases with complete data OR, 1. We then used weighted logistic regression to examine the association between sex and depression after stroke, and estimated 3 sequential models. Prevalence of depression at 90 days was The age-adjusted odds ratio OR of depression after stroke comparing women and men was 1. Compared with men, women were older, had lower educational attainment and greater stroke severity, and were more likely to be widowed and to have more prestroke functional limitations and cognitive impairment.

from weighted logistic regression models of Corpus Christi date now association between sex and depression after stroke, Brain Attack Surveillance in Corpus Christi project, United States, — Stratum-specific odds ratios OR of depression at 90 days poststroke comparing women with men by prestroke depression status, Brain Attack Surveillance in Corpus Christi project, United States, — Among participants with no history of depression, approximately two-fifths were women table e-5, doi. The most prevalent symptoms in both sexes were fatigue and sleep disturbance, which could be depressive symptoms, direct complications of stroke, or both.

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